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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Integrated genomics analysis highlights important SNPs and genes implicated in moderate-to-severe asthma based on GWAS and eQTL datasets

Fig. 3

Consistent findings of severe asthma-relevant risk genes from independent datasets. a Venn plot of severe asthma-relevant genes based on four datasets: Dataset #1 (MAGMA analysis), Dataset #3 (Sherlock analysis), Dataset #4 (Sherlock analysis), and Dataset #5 (Sherlock analysis). There were 11 promising genes validated among all four datasets. b In silico permutation analysis (100,000 times) of the counts of risk genes from Dataset #3 overlapped with that from Dataset #4. c In silico permutation analysis (100,000 times) of the counts of risk genes from Dataset #3 overlapped with that from Dataset #5. d In silico permutation analysis (100,000 times) of the counts of risk genes from Dataset #3 overlapped with genes from MAGMA analysis of Dataset #1

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BMC Pulmonary Medicine

ISSN: 1471-2466

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