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Categories
|
Sensitivity (%)
|
Specificity (%)
|
PLR
|
NLR
|
PPV (%)
|
NPV (%)
|
|---|
|
FeNO > 20 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
69.71
|
64.25
|
1.9
|
0.5
|
51.31
|
79.70
|
|
B-Eos > 200 cells/μl*
|
56.07
|
81.10
|
3.0
|
0.5
|
61.58
|
77.36
|
|
B-Eos > 300 cells/μl*
|
41.83
|
89.93
|
4.2
|
0.6
|
69.18
|
74.10
|
|
B-Eos > 400 cells/μl*
|
31.89
|
93.22
|
4.7
|
0.7
|
71.77
|
71.70
|
|
B-Eos > 500 cells/μl*
|
22.57
|
95.55
|
5.1
|
0.8
|
73.25
|
69.55
|
|
FeNO > 30 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
58.95
|
80.39
|
3.0
|
0.5
|
61.89
|
78.38
|
|
B-Eos > 200 cells/μl*
|
47.42
|
89.63
|
4.6
|
0.6
|
71.19
|
75.93
|
|
B-Eos > 300 cells/μl*
|
35.38
|
94.47
|
6.4
|
0.7
|
77.58
|
73.01
|
|
B-Eos > 400 cells/μl*
|
26.97
|
96.28
|
7.3
|
0.8
|
79.67
|
70.93
|
|
B-Eos > 500 cells/μl*
|
19.09
|
97.56
|
7.8
|
0.8
|
80.85
|
69.05
|
|
FeNO > 40 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
50.98
|
90.38
|
5.3
|
0.5
|
74.12
|
77.33
|
|
B-Eos > 200 cells/μl*
|
41.00
|
94.92
|
8.1
|
0.6
|
81.33
|
74.86
|
|
B-Eos > 300 cells/μl*
|
30.59
|
97.29
|
11.3
|
0.7
|
85.92
|
72.18
|
|
B-Eos > 400 cells/μl*
|
23.32
|
98.18
|
12.8
|
0.8
|
87.36
|
70.32
|
|
B-Eos > 500 cells/μl*
|
16.51
|
98.80
|
13.8
|
0.8
|
88.16
|
68.65
|
|
FeNO > 50 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
43.09
|
93.87
|
7.0
|
0.6
|
79.16
|
75.32
|
|
B-Eos > 200 cells/μl*
|
34.66
|
96.76
|
10.7
|
0.7
|
85.25
|
73.27
|
|
B-Eos > 300 cells/μl*
|
25.86
|
98.27
|
15.0
|
0.8
|
89.00
|
71.04
|
|
B-Eos > 400 cells/μl*
|
19.72
|
98.84
|
17.0
|
0.8
|
90.16
|
69.50
|
|
B-Eos > 500 cells/μl*
|
13.95
|
99.24
|
18.3
|
0.9
|
90.80
|
68.10
|
|
FeNO > 60 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
35.31
|
96.09
|
9.0
|
0.7
|
83.00
|
73.33
|
|
B-Eos > 200 cells/μl*
|
28.40
|
97.93
|
13.7
|
0.7
|
88.13
|
71.68
|
|
B-Eos > 300 cells/μl*
|
21.19
|
98.90
|
19.2
|
0.8
|
91.23
|
69.90
|
|
B-Eos > 400 cells/μl*
|
16.16
|
99.26
|
21.8
|
0.8
|
92.17
|
68.66
|
|
B-Eos > 500 cells/μl*
|
11.43
|
99.51
|
23.5
|
0.9
|
92.69
|
67.53
|
|
FeNO > 70 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
28.76
|
97.62
|
12.1
|
0.7
|
86.73
|
71.72
|
|
B-Eos > 200 cells/μl*
|
23.13
|
98.74
|
18.4
|
0.8
|
90.86
|
70.39
|
|
B-Eos > 300 cells/μl*
|
17.26
|
99.33
|
25.8
|
0.8
|
93.30
|
68.96
|
|
B-Eos > 400 cells/μl*
|
13.16
|
99.55
|
29.2
|
0.9
|
94.04
|
67.96
|
|
B-Eos > 500 cells/μl*
|
9.31
|
99.70
|
31.4
|
0.9
|
94.44
|
67.05
|
|
FeNO > 80 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
24.26
|
98.35
|
14.7
|
0.8
|
88.83
|
70.62
|
|
B-Eos > 200 cells/μl*
|
19.51
|
99.13
|
22.4
|
0.8
|
92.37
|
69.51
|
|
B-Eos > 300 cells/μl*
|
14.56
|
99.54
|
31.4
|
0.9
|
94.43
|
68.31
|
|
B-Eos > 400 cells/μl*
|
11.10
|
99.69
|
35.5
|
0.9
|
95.05
|
67.48
|
|
B-Eos > 500 cells/μl*
|
7.85
|
99.79
|
38.3
|
0.9
|
95.39
|
66.72
|
|
FeNO > 90 ppb†
| | | | | | |
|
B-Eos > 100 cells/μl*
|
19.75
|
98.85
|
17.2
|
0.8
|
90.26
|
69.51
|
|
B-Eos > 200 cells/μl*
|
15.89
|
99.39
|
26.1
|
0.8
|
93.38
|
68.62
|
|
B-Eos > 300 cells/μl*
|
11.85
|
99.68
|
36.6
|
0.9
|
95.18
|
67.67
|
|
B-Eos > 400 cells/μl*
|
9.04
|
99.78
|
41.4
|
0.9
|
95.72
|
67.00
|
|
B-Eos > 500 cells/μl*
|
6.40
|
99.86
|
44.6
|
0.9
|
96.02
|
66.38
|
|
FeNO > 38 ppb‡
| | | | | | |
|
B-Eos > 203 cells/μl‡
|
42.18
|
94.41
|
7.6
|
0.6
|
80.31
|
75.14
|
- †Baseline screening value of the former biomarker
- *Progressively increasing cutoff values of the combined biomarkers
- ‡The optimal diagnostic cutoff value for each biomarker alone
